I     Projects of fundamental and applied research, joint projects and doctorate degree projects in the area of HIV/AIDS, viral hepatitis, tick-borne encephalitis and diphtheria financed by the Latvian Cuncil of Science. The most significant projects are the following:

1.       Joint Project Nr.06.0035 „Acute and chronic infections: mechanisms of infectious agents pathogenicity, persistence and resistance development, ways to effective diagnostics and treatment” (directors: prof. L.Vīksna, assoc.prof. A.Martinsons) and its subprojects:

·         Nr.06.0035.01 „Introduction of molecular approaches into diagnostics, prognostics, therapy, and containment of viral hepatitis (director prof. L.Vīksna).

·         Nr.06.0035.02 „Tick-borne encephalitis: nitric oxide metabolism and its clinical, biochemical and immunological consequences” (director prof. B.Rozentāle).

·         Nr.06.0035.04 „Investigation of HLA II class antigens molecular structures and its associations with the different clinical forms of HCV infection. Immunoethiopatogenesis studies” (directors: prof. A.Sochnevs, prof. L.Vīksna).

·         Nr.06.0035.05 „Study of HIV-1 mutation pattern associated with drug resistance in Latvia” (director prof. L.Vīksna).

2.       Projects:  

·         Nr.04.1344 „Hepatitis C virus (HCV) infection: qualitative and quantitative aspects of HCV persistence (directors prof. L.Vīksna, Dr.biol. I.Sominska).

·         Nr.05.1821 „Transformation of liver in hepatitis C virus (HCV) infection: pathomorphological mechanisms, clinical, bichemical and immunological consequences (director Dr.med. V.Sondore).

·         Nr.04.1203 „Damages of central nervous system due to excessive increase of manganese in the body, clinical signs and symptoms and evaluation of treatment effectiveness with antidotes (helatores)” (director assoc.prof.V.Liguts, director in ICL – prof. B.Rozentāle).

II       Clinical trials in drug research.

III     Applied research in infectious diseases to develop the definite questions regarding to pathogenesis, diagnostics and therapy of infectious diseases (studies in the area of liver fibrosis and cell apoptosis).

IV     Basic and applied research in infectious diseases (international projects):

·        The Euro SIDA network 2001-2006. Clinical and virological outcome of European patients infected with HIV (joint project with Hvidovre University, Denmark; director in ICL – prof. L.Vīksna).

·        European Network for diagnostics of „Imported” Viral Diseases (ENIVD); project together with Robert Koch Institute, Germany; director in ICL – prof. B.Rozentāle.

·        SPREAD (Strategy to Control Spread of HIV Drug Resistance). EC programme, director in ICL – prof. B.Rozentāle.

The results of these research projects are reflected in various forms of publications – in local and internationally cited articles and in other materials (abstracts, proceedings, reports). Particular novelties and findings are made ready for patenting.

The dedicated personnel of the Infectology Center of Latvia actively takes part in various international, scientific and practical forums to discuss and solve various types of topical infectology problems. The Center has organized various international congresses, symposiums, workshops and seminars, such as – 2nd and 7th Nordic-Baltic Congress on Infectious Diseases in 1996, 2006, Vaccination Day (in 1999, 2001, 2003, 2005), Baltic States’ Congress on Hepatology in 2002, 3rd Baltic Region Conference „Together Against AIDS!” in 2003 and more.

ICL also serves as a base for the training of infectology residents, family doctors, and lab specialists. In addition, it also serves as a base for scientific and practical activites for professional associations such as Latvian Infectologists Association, the Latvian Hepatologists Association, and partially for the other professional associations (laboratory specialists).

To promote the Professional development of young specialists in infectious diseases, annual scientific and practical conferences are organized at the Infectology Center of Latvia, in which young colleagues lecture about current infectology problems.